|DRUGCOAT SERIES||MONOGRAPHS||PHYSICAL FORM||DISSOLUTION PROPERTIES|
|DRUGCOAT E 100||
USP/NF: Amino Methacrylate Copolymer
Ph. Eur.: Basic Butylated Methacrylate Copolymer
Dissolve up to pH 5.0
Soluble in Gastric Fluid
|DRUGCOAT E PO||Powder|
|DRUGCOAT E 12.5||Organic Solution 12.5%|
- pH Dependent Drug release
- Protection of API from environmental factors
- Improves patient compliance
- Lowest WVTR in its Class
- Moisture Protection
- Higher stability
- Taste and Odor Masking
- Improve storage stability of Sensitive API's
It is recommended to add 10-20% plasticizer on dry polymer substance into the DRUGCOAT E Series Solution or Dispersion to obtain films adequate flexibility.
Glidants like Talc, Micronized amorphous silica and Glycerol Monostearate facilitates spray application to the cores.
Opaque white or colored coating can be obtained by adding pigments like Iron Oxide and Lakes.
Solvents For Non Aqueous Base
Isopropyl alcohol and acetone, also mixture of these
Powder/ Granules: 10 kg net in Paper fiber drum with polyethylene lining.
Organic Solution: 25kg net in drum.
Store at controlled room temperature. (USP, General Monograph)